Studies show benefits and risks of testosterone treatment in older men
00:22, Feb 25, 2017
Copyright 2015 All rights reserved. This material can't be published, transferred, copied or redistributed.
Indeed, another trial published Tuesday, which was not part of the TTrials, showed a lower risk of cardiovascular events, including heart attack or stroke, in men who'd received testosterone, on average, for 3.4 years.
Testosterone had no effect on memory or mental function, based on tests given before, halfway and at the end of treatment to almost 500 men with age-related memory decline. Co-author and researcher of the study, Ronald S. Swerdloff, MD, of LA BioMed noted that "We want to emphasize that this study was exploratory and emphasizes the need for a large-scale, well-controlled, long-term safety trial to determine if there is an increased risk of heart damage or death". Studies of the risks and benefits have been mixed, and the Food and Drug Administration beefed up its warnings about cardiac side effects of testosterone supplementation in 2015.
The results showed that after an year of testosterone treatment, men over 65 years of age with low testosterone significantly increased bone density and estimated bone strength compared to those on placebo. In addition to low testosterone, the presence of complaints such as low sexual function, difficulty in walking or low vitality was required for eligibility to participate in the trials. Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone. After one year of treatment, 54 percent of the men with unexplained anemia and 52 percent of those with anemia from known causes had clinically significant increases in hemoglobin (red blood cell) levels, compared with 15 percent and 12 percent, respectively, of those in the placebo group. The results were greater in the spine than the hip.
"Final decisions about testosterone treatment for older men will depend on balancing the results from these seven TTrials with the results from a much larger and longer term trial created to assess cardiovascular and prostate risk in the future", said Snyder.
Jamie Chung to Play Blink in Fox's Marvel Pilot From Bryan Singer
Chung appeared as Mulan on ABC's Once Upon a Time and is set to portray a recurring role on the upcoming season of Casual in Hulu. This would allow alternate versions of popular X-Men characters-maybe played by other actors-who aren't too big to do a TV show.
The first published research from the TTrials past year reported on some of the benefits to testosterone treatment.
However, the study of 8,808 men was observational. After 12 months, they found that the testosterone group had better bone density and a reduced risk of developing anaemia.
In decades of research, scientists have found only one medical condition that's clearly and effectively treated with testosterone supplements: pathological hypogonadism-that's low testosterone levels due to disease of the hypothalamus, pituitary gland, or testes.
That's why some doctors prescribe testosterone replacement. And other drugs may be more effective at treating anemia and improving bone mass than testosterone.
ELLENBERG: The volume of plaque increased more on the testosterone arm than on the placebo arm.
How do you know if you have low testosterone? "Maybe testosterone could be a reasonable substitute for all three".
How this flu season stacks up to past seasons: 5 key metrics
"Influenza vaccines are effective at reducing the risk of a person getting the flu and having to go to the doctor by about half". Children under age 5, adults 65 and older, pregnant women and people with certain medical conditions are most at risk.
But for cardiovascular health, there was an effect-a bad one.
Four clinical trials examine the effect of testosterone therapy in men aged 65 and older.
"I would say, ‚We have uncertainty about the health effects of testosterone and your risk of heart attacks". Having low testosterone can deflate your libido and leave you more susceptible to fractures. Testosterone treatment didn't improve patients' cognitive function, and it increased the amount of plaque buildup in the participants' coronary arteries. Those changes could signal increased chances for heart attacks although none occurred in the study.
NEIGHMOND: Longer-term research is needed, she says, to make sure stronger bones mean fewer fractures as men age.
Dr. Sergei Romashkan is chief of the clinical trials branch in the NIA's division of geriatrics and clinical gerontology. "The overall health benefits, however, remain to be determined", the researchers said.
The producers of the next "X-Men" movie are banking on the familiarity Simon Kinberg has with the "X-Men" franchise. Obviously, the movie wasn't what we wanted it to be and it wasn't received the way we wanted it to be.
Stricter safety standards after the 2011 Fukushima nuclear accident in Japan added to the cost of plants in China and the U.S. It is also moving to spin off its memory chip business to fix its battered balance sheet.
Mexican President Enrique Pena Nieto last month canceled a meeting after Trump insisted he would make Mexico pay for the wall. An undocumented Mexican immigrant committed suicide half an hour after he was deported from the United States, BBC reports.
He says she is waiting for her parents to arrive there from the south-central Mexican state of Guanajuato to meet her. Police ultimately removed the protester from the wheel, arrested a total of six people, and the van drove away.
In terms of Connectivity Options, the K10 (2017) supports Hybrid dual-SIM dual standby using the (nano-SIM + nano-SIM) slot. LG is also offering on-screen emergency icon to initiate the emergency call directly by tapping on the icon.
On Tuesday night, the brand unveiled its three covers of model Kate Upton along with peeks at the other stars of the issue. One of the major highlights for Williams was getting to wear a thong bikini, which she has never done before.
Wizards Acquire Bojan Bogdanovic From Nets
The Nets were reportedly "determined" to get a first for Bogdanovic, who is set to be a restricted free agent. Washington signed the 27-year-old Nicholson to a four-year deal in free agency but have played him sparingly.
Jimmy Kimmel wants a 'little more free time'
That said, the head writer on his show will be preparing some timely gags the night before. Here's what he recently had to say about why he might quit the game in the near future.
Chelsea gets Man United in FA Cup Q-Final
I scored twice and we played well. "(Ibrahimovic) made it look easy but the finish, when you're in the situation, is hard to take. The Manchester United striker has missed the last three games, including Sunday' s 2-1 win at Blackburn Rovers .
Hot felon attacks runway
Jeremy Meeks' mugshot went viral in 2014 after he was arrested for possession of firearms and criminal street gang activity. Backstage, he was the most-wanted model, showing off his tattoos and Plein briefs against a chain-link fence.
Yikes: Border Wall Just Got A Lot More Expensive
The report estimated that agreement alone could bring the cost from $11 million per mile to $15 million per mile in one area. The cost estimate in the leaked report is much higher than previous claims by both Trump and prominent Republican leaders.
Thomas Cook pretax loss widens as costs rise
Therefore Thomas Cook expects the Group's positive performance to be weighted more towards the second half than usual. However, UK bookings for the key summer period are now flat, with average selling prices two per cent higher.